Members-only rates
4.5 / 5 Excellent

21C Museum Hotel St Louis

21C Museum Hotel St Louis
21C Museum Hotel St Louis – St. Louis, MO
21C Museum Hotel St Louis – St. Louis, MO
Check in 4:00 PM
Check out 11:00 AM

About 21C Museum Hotel St Louis

Elegant Accommodations 21c Museum Hotel St Louis in Saint Louis offers stylish rooms with air-conditioning, private bathrooms, and modern amenities. Each room includes a work desk, free WiFi, and a seating area. Exceptional Facilities Guests can enjoy spa facilities, a wellness center, indoor swimming pool, and a terrace. Additional amenities include a fitness room, hot tub, and yoga classes. Dining Experience The modern restaurant serves Spanish cuisine for dinner, complemented by a bar. American breakfast is available each morning. Prime Location Located 1.2 mi from the Gateway Arch and near attractions such as Laclede's Landing and Forest Park. St. Louis Lambert International Airport is 13 mi away.

Amenities

  • On-site parking
  • 24-hour front desk
  • Meeting space
  • Fitness center
  • On-site dining
  • Valet parking
  • Bar / lounge
  • Café / coffee shop
  • Breakfast available
  • Business center
  • Concierge
  • Dry cleaning
  • Self-service laundry
  • Luggage storage
  • Full kitchen / kitchenette
  • In-room refrigerator
  • Pool
  • Spa / sauna
  • Pet friendly
  • Wheelchair accessible
  • Smoke-free property
  • Air conditioning
  • Elevator
  • In-room safe

Reviews

4.5 / 5
Excellent 2122 reviews
  • Engine customer Oct 2026

    Room was clean amenities were okay but the tub shower head and tap were not functioning properly. I was not able to turn it to tap fromshower head.

  • Engine customer Oct 2026

    Room clean. Staff friendly.

  • Engine customer Oct 2026

    We loved the whole experience We got there late so a lot of the stuff was closed and we didn't get to use or see because checkout is so early

  • Engine customer Oct 2026

    Overall, lovely stay and great staff. Beautiful hotel. Please check the tightness of the safety handrails in the shower in room 1012. they were loose.

  • Engine customer Sep 2026

    Fun hotel. Nice restaurant. I did not use the pool. Good location. Front desk pleasant and helpful.

  • Engine customer Sep 2026

    Exceptional

  • Engine customer Sep 2026

    The staff was wonderful

  • Engine customer Sep 2026

    Such a cool and trendy boutique hotel with all the amenities. Beautiful building. Paid parking around d the corner. 20 minutes walk to the Gateway Arch. So nice to get back to the hotel in the evening, have a few drinks at the bar and finish the evening with a visit to the pool area with hot tub, sauna, and steam room as well as the lap pool. Staff were incredible, so friendly and knowledgeable. Kristos and all the other bartenders were super friendly and made us some great cocktails. Would definitely recommend to friends and family and would stay again if we were back in the area.

  • Engine customer Sep 2026

    Room was clean, staff were helpful, Art was really neat. Also one of the nicest hotel gyms I’ve ever experienced. Very large pool and hot plus other spa accommodations. Overall really enjoyed our stay here and would definitely go back.

  • Engine customer Sep 2026

    Wonderful, fun place to stay! Staff was great. Clean and inviting with amazing art. And want to return!

  • Engine customer Sep 2026

    A bit off the beating path, but well worth the walk or ride there. Unfortunately I was only there for a day, so missed out on many of the amenities. But will definitely book here again and take advantage of all they have to offer. P.S. The room are well kept, roomy, and comfortable.

  • Engine customer Sep 2026

    21C Museum St Louis is my favorite hotel. It is so vibrant. I love to swim and that YMCA pool built in the 1920s is gorgeous with hot tub and sauna. You get great coffee in the room, not the typical swill. The museum exhibits are thoughtfully curated and edgy. And they are featured in the old YMCA basketball court! Our room was lovely—the whole place is. This hotel is a destination for locals, it’s the place to be. Idol Wolf is the first outstanding restaurant experience I’ve had in a hotel.

  • Engine customer Sep 2026

    My friends and I had 2 rooms for a girls concert night. upon arrival 1 of the rooms was real hot, they let the front desk know before we left for the evening. When we got back after the concert the room was still hot. They called again and were told nobody entered the room because they were not there. Then were told that it was not a quick fix and there were no other rooms to switch them to. It sounded like they already knew the ax was broke. They could have gone to another hotel, but they didn’t have a car and it was late, they did adjust 1/2 off. They did sleep, but not well because it took a long time as it was really hot. The rest of the hotel was lovely as was the rest of the staff. Disappointed about the one room.

  • Engine customer Sep 2026

    Wonderful experience, very unique and so close to so much!

  • Engine customer Sep 2026

    The property it itself is beautiful and the staff was incredibly helpful from the Valet to housekeeping and front desk but it’s clear they have some operational issues that are impacting the timelines of housekeeping and the overall cleanliness of the guest room end public areas. Good property with a ton of potential just needs better management.

  • Engine customer Sep 2026

    Exceptional

  • Engine customer Sep 2026

    The location can be convenient if you are visiting the Gateway Arch or attending an event downtown, and for us it worked well because we could walk to the AC/DC concert. Otherwise, there is not much happening immediately around the hotel, and the area did not feel nearly as welcoming or comfortable as other parts of St. Louis. If location had not been so important for this trip, we likely would have changed hotels after the first night and stayed closer to the Kingside Diner/Central West End area, which felt much more lively, cozy, and comfortable for walking around. The biggest disappointment was the lack of attention to detail and maintenance. The AC filter in our room was extremely dirty and looked long overdue for replacement. There were also broken fixtures/supports and issues with the bathroom door. Those are the kinds of things I would not expect to encounter at a hotel positioning itself as a 4-star property. Service also lacked the warmth and attentiveness that normally distinguish a higher-end hotel experience. The bar has a fun concept, but the food felt overpriced for what was delivered. The complimentary bourbon shot is also a clever marketing idea, although calling what was served a “shot” was generous - it was closer to half of one.

  • Engine customer Sep 2026

    Great location, spacious room.

  • Engine customer Sep 2026

    peaceful & enriching

  • Engine customer Sep 2026

    Nice room, super cozy bed, and very close to a lot of things downtown. Restaurant was fine. TV streaming didn't work, no ice machines small complaints. Otherwise great stay and loved our choice.

Frequently asked questions about 21C Museum Hotel St Louis

Does 21C Museum Hotel St Louis have free Wi-Fi?
Yes, 21C Museum Hotel St Louis offers free Wi-Fi for all guests.
Does 21C Museum Hotel St Louis offer parking?
Yes, 21C Museum Hotel St Louis offers both self-parking and valet parking. Fees may apply.
Does 21C Museum Hotel St Louis have meeting spaces, conference centers, or conference rooms?
Yes. 21C Museum Hotel St Louis offers banquet and reception facilities for events and group gatherings.
Does 21C Museum Hotel St Louis have a fitness center?
Yes, 21C Museum Hotel St Louis features an on-site fitness center for guests. Additional wellness amenities include spa, sauna, pool.
Where is 21C Museum Hotel St Louis located, and how walkable is the area?
21C Museum Hotel St Louis is located at 1528 Locust street, St. Louis, MO 63103. With a Walk Score of 89, the area is rated Very Walkable. Most errands can be completed on foot, with public transit and rideshare easily accessible.

What's nearby

Map of points of interest near 21C Museum Hotel St Louis
  • America's Center Convention Complex 0.6 mi
  • Pruitt–Igoe 0.8 mi
  • Louisiana Territory 1.0 mi
  • Gateway Arch 1.1 mi
  • Missouri Botanical Garden 3.3 mi
  • Washington University in St. Louis 5.6 mi

Why no public rates?

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